The terminus of CA 101, crisscrossed by both the Franklin/Gough and Fell/Oak corridors, and serviced by Muni Metro, Buses and Streetcars - Hayes Valley is one of the most accessible neighborhoods in the city.
A primary center of fine arts (Opera, Ballet and Symphony) and boutique shopping - a variety of clothing and shoe boutiques, and Dark Garden corsets. Blue Bottle Coffee keeps things moving, check it out.
Wikipedia: http://en.wikipedia.org/wiki/Hayes_Valley,_San_Francisco,_California